Relationship Between Age and Severity of Cognitive Impairment at Diagnosis For Early‐Onset and Late‐Onset Alzheimer’s Disease: Comparison of LEADS and ADNI

Abstract

Background: Research into AD has revealed that cognitive manifestation tends to differ depending on age of onset, such that younger patients often present with worse cognitive abilities than their older counterparts until the age of 75 – with a reversal of the relationship after 75‐years‐old (Barnes et al., 2018).