MechanismsHumans
Longitudinal relationships between systemic inflammatory markers, plasma p ‐tau181 and entorhinal tau Positron Emission Tomography (PET)
AAIC 2025 Abstract
Abstract
Background: Plasma levels of tau phosphorylated at threonine 181 ( p ‐tau181) become elevated before cortical tau and Alzheimer’s Disease (AD) pathology. Associations between systemic inflammation and AD biomarkers are conflicting and suggest protective and disease‐promoting effects.
The paper
Koral V Wheeler, Danielle Luu, Victoria R. Tennant, Meredith N. Braskie
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Noelle N. Lee, Marylan Davison, Maxwell W Hand, Arthur W. Toga, Sid E. O’Bryant, Kristine S. Yaffe,University of Southern California
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025



