Longitudinal relationships between systemic inflammatory markers, plasma p ‐tau181 and entorhinal tau Positron Emission Tomography (PET)

AAIC 2025 Abstract

Abstract

Background: Plasma levels of tau phosphorylated at threonine 181 ( p ‐tau181) become elevated before cortical tau and Alzheimer’s Disease (AD) pathology. Associations between systemic inflammation and AD biomarkers are conflicting and suggest protective and disease‐promoting effects.

The paper