Association Between Vascular Risk Factors and White Matter Integrity Among Diverse Middle‐Aged and Older Hispanic/Latino Adults from the SOL‐INCA‐MRI study

Abstract

Background: Cerebral small vessel disease (SVD) is characterized by white matter hyperintensities (WMH) and microstructural damage detectable via diffusion‐weighted imaging (DWI) parameters such as free water (FW) and fractional anisotropy (FA). Vascular risk factors contribute to white matter damage and cognitive decline.