A blood lipidomic score and Alzheimer’s disease: associations and mediating mechanisms from two cohort studies

Abstract

Background: Dyslipidemia is a risk factor for Alzheimer's disease (AD). This study was to develop a blood lipid score (BLS) of lipidomics and investigate its associations with incident risk and endophenotypes of AD in older adults. Methods: The BLS associated with AD was developed using Cox proportional hazard regression.