Sex Hormones and Cerebrovascular Health: Implications for Dementia Risk Across the Lifespan

Abstract

Background: Circulating sex hormones decrease in aging, influencing cerebrovascular health, a key factor in dementia risk. Early menopause is a risk factor for dementia comparable to smoking ² . Estradiol consistently supports female vasculature ¹ and brain health, though its effects on cerebrovascular health is understudied.