Ponderal index at birth and late life DNA methylation signature and its influence in cognition function: insights from the Age, Gene/Environment Susceptibility–Reykjavik Study

Abstract

Background: A growing body of evidence suggests that an adverse prenatal environment is linked to poor health outcomes in later life. We performed birth‐size EWAS and developed a score and evaluated its relationship with cognitive function. Method: We analyzed data from 795 participants (mean age: 75.3 years; 58.