Associations between plasma biomarkers and longitudinal neuropsychiatric symptoms across the cognitive spectrum in older adults: findings from the Massachusetts Alzheimer's Disease Research Center

Abstract

Background: Neuropsychiatric symptoms (NPS) are common in the preclinical and prodromal stages of Alzheimer's Disease and Related Dementias (ADRD) and are associated with cognitive and functional decline. However, the neurobiology of these symptoms and prognostic markers of their emergence are not well understood.

The paper