AAIC 2025 Abstract

Association between diurnal core body temperature rhythm and diurnal variation in blood biomarkers of dementia

Study in peopleMechanisms

Abstract

Background: Core CSF and plasma biomarkers of Alzheimer's Disease (AD) Aβ40, Aβ40, total tau and Ptau‐217 exhibit a diurnal pattern, being higher in the evening vs morning in most, but not all reports. The mechanisms underlying this pattern remain unknown.

The paper