Evaluating Plasma Ptau‐217 Sensitivity in Detecting Individual Differences in Early‐stage Tau Aggregation in Cognitively Unimpaired Older Adults

Abstract

Background: Plasma ptau‐217 is a promising biomarker for detecting Alzheimer's pathology. However, previous studies show no or weak correlations between plasma ptau‐217 and tau‐PET in cognitively unimpaired (CU) individuals.