AAIC 2025 Abstract
Cerebrovascular disease and neuroinflammation predict change in Alzheimer's disease plasma biomarkers in adults with Down Syndrome
Study in peopleMechanisms
Abstract
Background: Adults with Down syndrome (DS) develop Alzheimer's disease (AD) pathology by age 40, despite few vascular risk factors. MRI shows cerebrovascular disease (CVD) that precedes or begins contemporaneously with markers of AD pathology.
