AAIC 2025 Abstract

Exploring the role of MRI to optimize the design of clinical trials for progressive supranuclear palsy and corticobasal degeneration

Study in peopleBiomarkers

Abstract

Background: Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are severe neurodegenerative disorders lacking disease‐modifying treatments and validated biomarkers. Clinical trials face challenges due to phenotypic overlap and imperfect clinicopathological correlations.

The paper