Cortical asymmetry index in Autosomal Dominant Alzheimer's Disease: insights from the Clínic Barcelona and DIAN cohorts over time

Abstract

Background: The Cortical Asymmetry Index (CAI) evaluates brain asymmetry, showing increased asymmetry in sporadic Alzheimer's Disease (AD). We investigate CAI in asymptomatic (AMC) and symptomatic (SMC) mutation carriers of Autosomal Dominant Alzheimer's Disease (ADAD).