BiomarkersHumans
Effect of Corpulence on pTau217 Measurements in Plasma
AAIC 2025 Abstract
Abstract
Background: Plasma pTau217 is a robust indicator of amyloid pathology recently included as a Core 1 biomarker for Alzheimer's disease (AD). However, factors like body mass can influence its measurement. Investigation of how much this impacts classification of participants as Core 1 A+ is relevant for studies looking at early AD stages.
The paper
Ramiro Eduardo Rea Reyes, Rachael E. Wilson, Julie Elisabeth Oomens, Sterling C. Johnson
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Rachel L Studer, Elysse Keske, Aaron Fredricks, Martie Marshall, Cindy Jensen, Monica VandenLangenberg, Beckie Jeffers, Erin McMullen Jonaitis, Rebecca E. Langhough, Nathaniel A. Chin, Sanjay Asthana, Henrik Zetterberg,University of Wisconsin–Madison
AAIC 2025 Abstract · 24 Dec 2025 · CC BY
Presented at AAIC 2025
