Risk factors and clinical relevance of MRI vascular markers in the U.S. POINTER study: a cross‐cohort comparison with the Framingham Heart Study

Abstract

Background: Our objective is to examine the generalizability of the relationships between four MRI markers of CVD: DTI‐derived free water (FW), fractional anisotropy (FA), perivascular space (PVS) and white matter hyperintensities (WMH) volume, with vascular risk factors (VRF) and cognition in the baseline POINTER Imag