AAIC 2025 Abstract

Genetic architecture of the limbic white matter microstructure in aging and Alzheimer's Disease

Study in peopleMechanisms

Abstract

Background: Limbic white matter (WM) abnormalities are strongly elevated along the Alzheimer's Disease (AD) diagnostic continuum, but the underlying biological mechanisms remain unclear. This study aims to conduct a large‐scale genetic analysis of WM microstructure in older adults.

The paper