AAIC 2025 Abstract

Molecular signatures of LATE‐NC: insights from transcriptomic analyses

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Abstract

Background: Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathological change (LATE‐NC) is the third most significant contributor to late‐onset dementia after Alzheimer's disease neuropathologic change (ADNC; amyloid‐β and tau) and cerebrovascular disease.

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