AAIC 2025 Abstract
Heterogeneity in the Genetic Architecture of Alzheimer disease (AD) across Ancestry Groups
By Penelope H. Benchek, Christiane Reitz, Sven-Thorsten Dietrich, Show 15 more authorsWilliam S Bush
Study in peoplePopulations
Abstract
Background: In AD genomics research there are known differences in AD prevalence across Non‐Hispanic White (NHW), African American (AA), Asian American (AsA) and Hispanic/Latino (HL) ancestry groups, and paradoxical differences in effect size of APOE (larger effects in groups with lower prevalence).
