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AAIC 2025 Abstract

Covid‐19 Spike protein impact on Alzheimer's (AD) and Cerebrovascular Disease

By Sally Ann Frautschy, Kapil Manglani, Xiaohong Zuo, Show 5 more authorsGregory M. Cole
Experiments in animalsMechanisms
Paper

Abstract

Background: Most COVID‐19 cases fully recover, but 7% report persistent symptoms (Long Covid, LC). SARS‐CoV2 uses surface S1 Spike protein to bind ACE2 receptors leading to sustained complement activation.

The paper

Sally Ann Frautschy, Kapil Manglani, Xiaohong Zuo, Show 5 more authorsGregory M. Cole

University of California, Los Angeles

AAIC 2025 Abstract, 24 Dec 2025, CC BY

Presented at AAIC 2025

doi.org/10.1002/alz70855_106266

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