AAIC 2025 Abstract

Leveraging Enhanced Hi‐C Capture Analysis (eHiCA) to identify susceptibility genes in ambiguous GWAS loci for Alzheimer's disease: evidence for known and unusual suspects

Experiments in cellsMechanisms

Abstract

Background: The identification of susceptibility genes in noncoding genome‐wide association study (GWAS) loci remains a challenge as interactions between regulatory elements and targets can span several Mb and exceed 1:1 ratio of element‐to‐target.

The paper