AAIC 2025 Abstract

LOAD3: A new preclinical mouse model that incorporates humanized APOE4 , Aβ and MAPT

Experiments in animalsMechanisms

Abstract

Background: The MODEL‐AD (Model Organism Development and Evaluation for Late‐Onset Alzheimer's Disease) Consortium is creating a new generation of mouse models for Alzheimer's disease (AD) based on genetic and environmental factors shown to increase risk for human AD.

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