APOE ‐ε4×Sex×SNP Interactions in Cognition: A Multi‐Cohort GWAS Meta‐Analysis

Abstract

Background: Two‐thirds of Alzheimer's disease (AD) patients are women, and sex‐specific APOE ‐related cognitive impairment is well‐documented. However, the interplay among APOE genotype, sex, and common genetic variants (SNPs) remains poorly understood, particularly for specific cognitive domains.

The paper