MechanismsAnimals

Humanized Klotho variants cause widespread transcriptional changes in B6 mice

AAIC 2025 Abstract

Abstract

Background: The VS haplotype of the longevity factor klotho (KL) has been associated with decreased risk of Alzheimer's Disease (AD) and reduced AD brain pathology.

The paper

Tyler AL, Garceau D, Kotredes KP et al.

AAIC 2025 Abstract · 23 Dec 2025 · CC BY

Presented at AAIC 2025

doi.org/10.1002/alz70855_102892

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