AAIC 2025 Abstract
Association between soluble TREM2, APOE genotype, Alzheimer's copathology and disease evolution in dementia with Lewy bodies
By Pablo Zaragoza-Ballester, Briggitte Nuscher, Daniel Andres Alcolea, Show 11 more authorsEstrella Morenas-Rodríguez
Study in peopleMechanisms
Abstract
Background: APOEε4 is a genetic risk factor for both Alzheimer's Disease (AD) and dementia with Lewy bodies (DLB). TREM2‐dependent microglial activation is considered protective in AD and has been proposed to interact with APOE in this context.
