AAIC 2025 Abstract

Sex Differences in the Diffusion of Tau Neurofibrillary Tangles Across Functional Brain Networks

Study in peopleMechanisms

Abstract

Background: Alzheimer's disease is characterized by the accumulation and spread of tau neurofibrillary tangles across cortical regions, driving cognitive decline. However, many cortical regions exhibit little tau, despite their functional connections to regions with high levels.

The paper