https://agingresearch.news/p/MED-42785525 2026-10-03T00:10:06.517Z AgingResearch.News en 2026-10-03T00:10:06.517Z Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice https://agingresearch.news/p/MED-42785525/opengraph-image/card https://agingresearch.news/p/MED-42793202 2026-10-03T00:10:04.464Z AgingResearch.News en 2026-10-03T00:10:04.464Z Nuciferine reduces ovariectomy-induced bone loss in rats by activating autophagy https://agingresearch.news/p/MED-42793202/opengraph-image/card https://agingresearch.news/p/MED-42792120 2026-10-03T00:10:03.687Z AgingResearch.News en 2026-10-03T00:10:03.687Z Ergothioneine carbon dot nanozymes reduce intervertebral disc degeneration in an animal model https://agingresearch.news/p/MED-42792120/opengraph-image/card https://agingresearch.news/p/MED-42793265 2026-10-03T00:09:58.136Z AgingResearch.News en 2026-10-03T00:09:58.136Z Peroxisomal enzyme ACOX-1.2 enables extended lifespan in long-lived roundworms https://agingresearch.news/p/MED-42793265/opengraph-image/card https://agingresearch.news/p/MED-42792256 2026-10-03T00:09:57.187Z AgingResearch.News en 2026-10-03T00:09:57.187Z Antipsychotic drug pimozide extends lifespan and boosts stress resistance in nematodes https://agingresearch.news/p/MED-42792256/opengraph-image/card https://agingresearch.news/p/MED-42792251 2026-10-03T00:09:56.550Z AgingResearch.News en 2026-10-03T00:09:56.550Z Suppressing clk-1 restores lifespan and mitochondrial function in psd-1 deficient worms https://agingresearch.news/p/MED-42792251/opengraph-image/card https://agingresearch.news/p/MED-42789189 2026-10-03T00:09:56.522Z AgingResearch.News en 2026-10-03T00:09:56.522Z Erigeron breviscapus extends worm lifespan and reduces senescence markers in mice https://agingresearch.news/p/MED-42789189/opengraph-image/card https://agingresearch.news/p/MED-42791452 2026-10-03T00:09:51.068Z AgingResearch.News en 2026-10-03T00:09:51.068Z Dietary benefits on epigenetic aging may largely reflect familial factors https://agingresearch.news/p/MED-42791452/opengraph-image/card https://agingresearch.news/p/MED-42792858 2026-10-03T00:09:50.378Z AgingResearch.News en 2026-10-03T00:09:50.378Z Plasma metabolic shifts link to T-cell senescence and mortality in older COVID-19 patients https://agingresearch.news/p/MED-42792858/opengraph-image/card https://agingresearch.news/p/MED-42792976 2026-10-03T00:09:48.784Z AgingResearch.News en 2026-10-03T00:09:48.784Z Blood methylation clocks capture two distinct biological domains of aging https://agingresearch.news/p/MED-42792976/opengraph-image/card https://agingresearch.news/p/MED-42785437 2026-10-03T00:09:48.155Z AgingResearch.News en 2026-10-03T00:09:48.155Z Spiny mouse fibroblasts prefer glycolysis and resist oxidative stress across lifespan https://agingresearch.news/p/MED-42785437/opengraph-image/card https://agingresearch.news/p/MED-42792166 2026-10-03T00:05:07.011Z AgingResearch.News en 2026-10-03T00:05:07.011Z Senescent human astrocytes impair neuronal mitochondrial function through released factors https://agingresearch.news/p/MED-42792166/opengraph-image/card https://agingresearch.news/p/MED-42787268 2026-10-03T00:05:04.493Z AgingResearch.News en 2026-10-03T00:05:04.493Z Lifestyle modification reduces phenotypic age in adults with prediabetes https://agingresearch.news/p/MED-42787268/opengraph-image/card https://agingresearch.news/p/MED-42786149 2026-10-03T00:05:00.325Z AgingResearch.News en 2026-10-03T00:05:00.325Z Inotodiol preserves muscle mass and function in aged mice https://agingresearch.news/p/MED-42786149/opengraph-image/card https://agingresearch.news/p/MED-42786975 2026-10-03T00:04:57.097Z AgingResearch.News en 2026-10-03T00:04:57.097Z CD47 blockade reduces doxorubicin-induced cardiac aging in male mice https://agingresearch.news/p/MED-42786975/opengraph-image/card https://agingresearch.news/p/MED-42788688 2026-10-03T00:04:56.295Z AgingResearch.News en 2026-10-03T00:04:56.295Z Blind mole-rat mesenchymal stem cells resist carcinogen-induced damage through preserved p53 signaling https://agingresearch.news/p/MED-42788688/opengraph-image/card https://agingresearch.news/p/MED-42793066 2026-10-03T00:04:53.467Z AgingResearch.News en 2026-10-03T00:04:53.467Z MUTYH protects telomeres from chronic oxidative damage in cancer cells https://agingresearch.news/p/MED-42793066/opengraph-image/card https://agingresearch.news/p/MED-42792104 2026-10-03T00:04:50.465Z AgingResearch.News en 2026-10-03T00:04:50.465Z FUNDC1 protects skin against UVA damage through mitophagy and P53 stability https://agingresearch.news/p/MED-42792104/opengraph-image/card https://agingresearch.news/p/MED-42785600 2026-10-03T00:04:49.795Z AgingResearch.News en 2026-10-03T00:04:49.795Z Machine learning frailty index from healthcare claims predicts mortality and disability https://agingresearch.news/p/MED-42785600/opengraph-image/card https://agingresearch.news/p/MED-42792185 2026-10-03T00:04:49.150Z AgingResearch.News en 2026-10-03T00:04:49.150Z Proteasome activity maintains red blood cell integrity during storage and restoration https://agingresearch.news/p/MED-42792185/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328102 2026-10-03T00:04:47.316Z AgingResearch.News en 2026-10-03T00:04:47.316Z Interferon-responsive oligodendrocytes emerge during white matter aging in killifish https://agingresearch.news/p/PPR-PPR1328102/opengraph-image/card https://agingresearch.news/p/MED-42790614 2026-10-03T00:00:05.044Z AgingResearch.News en 2026-10-03T00:00:05.044Z Intranasal Arc-engineered exosomes reduce Alzheimer pathology by restoring autophagy https://agingresearch.news/p/MED-42790614/opengraph-image/card https://agingresearch.news/p/MED-42788342 2026-10-03T00:00:02.398Z AgingResearch.News en 2026-10-03T00:00:02.398Z Activating Sirt1 reduces aortic valve calcification in mice and human cells https://agingresearch.news/p/MED-42788342/opengraph-image/card https://agingresearch.news/p/MED-42790827 2026-10-03T00:00:01.756Z AgingResearch.News en 2026-10-03T00:00:01.756Z Blocking Src kinase reduces neuroinflammation by activating microglial mitophagy in mice https://agingresearch.news/p/MED-42790827/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328217 2026-10-03T00:00:01.636Z AgingResearch.News en 2026-10-03T00:00:01.636Z Microplastics induce cellular senescence and alter network activity in human brain organoids https://agingresearch.news/p/PPR-PPR1328217/opengraph-image/card https://agingresearch.news/p/MED-42790826 2026-10-02T23:59:55.906Z AgingResearch.News en 2026-10-02T23:59:55.906Z Sephin1 promotes mitophagy and reduces alpha-synuclein toxicity in Parkinson models https://agingresearch.news/p/MED-42790826/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328378 2026-10-02T23:59:55.792Z AgingResearch.News en 2026-10-02T23:59:55.792Z Innate immune stress activation drives pathology caused by heterochromatin loss https://agingresearch.news/p/PPR-PPR1328378/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328435 2026-10-02T23:59:55.030Z AgingResearch.News en 2026-10-02T23:59:55.030Z Caloric restriction dynamically alters RNA splicing and lipid composition in mouse brains https://agingresearch.news/p/PPR-PPR1328435/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328384 2026-10-02T23:59:54.548Z AgingResearch.News en 2026-10-02T23:59:54.548Z A UHRF1 feed-forward mechanism sustains DNA methylation at CpG-sparse genomic regions https://agingresearch.news/p/PPR-PPR1328384/opengraph-image/card https://agingresearch.news/p/MED-42802938 2026-10-02T23:59:49.328Z AgingResearch.News en 2026-10-02T23:59:49.328Z Killifish exhibit distinct structural changes and fibrosis during cardiac aging https://agingresearch.news/p/MED-42802938/opengraph-image/card https://agingresearch.news/p/MED-42799693 2026-10-02T23:59:48.964Z AgingResearch.News en 2026-10-02T23:59:48.964Z Epigenetic age acceleration tracks lower baseline cognition and greater retest gains https://agingresearch.news/p/MED-42799693/opengraph-image/card https://agingresearch.news/p/MED-42798245 2026-10-02T23:59:48.842Z AgingResearch.News en 2026-10-02T23:59:48.842Z Astragaloside IV reduces cardiac aging in mice by restoring mitochondrial balance https://agingresearch.news/p/MED-42798245/opengraph-image/card https://agingresearch.news/p/MED-42796619 2026-10-02T23:59:47.847Z AgingResearch.News en 2026-10-02T23:59:47.847Z Baicalein reduces disuse-driven skeletal senescence and alters gut microbes in rats https://agingresearch.news/p/MED-42796619/opengraph-image/card https://agingresearch.news/p/MED-42799939 2026-10-02T23:55:06.175Z AgingResearch.News en 2026-10-02T23:55:06.175Z Lipid metabolism regulators and snoRNPs control mitochondrial surveillance and mitophagy https://agingresearch.news/p/MED-42799939/opengraph-image/card https://agingresearch.news/p/MED-42802377 2026-10-02T23:55:04.603Z AgingResearch.News en 2026-10-02T23:55:04.603Z Deep learning predicts mouse hematopoietic stem cell aging from chromatin architecture https://agingresearch.news/p/MED-42802377/opengraph-image/card https://agingresearch.news/p/MED-42801161 2026-10-02T23:55:02.764Z AgingResearch.News en 2026-10-02T23:55:02.764Z Age-linked immune profiles identify distinct risk groups for chronic obstructive pulmonary disease https://agingresearch.news/p/MED-42801161/opengraph-image/card https://agingresearch.news/p/MED-42794693 2026-10-02T23:55:02.752Z AgingResearch.News en 2026-10-02T23:55:02.752Z Targeted metal modulation preserves retinal structure and vision in zebrafish https://agingresearch.news/p/MED-42794693/opengraph-image/card https://agingresearch.news/p/MED-42800547 2026-10-02T23:54:56.836Z AgingResearch.News en 2026-10-02T23:54:56.836Z Arsenic triggers heart senescence in mice while quercetin counteracts the damage https://agingresearch.news/p/MED-42800547/opengraph-image/card https://agingresearch.news/p/MED-42801617 2026-10-02T23:54:56.796Z AgingResearch.News en 2026-10-02T23:54:56.796Z Encapsulated sustained-release whey protein improves muscle mass and strength in sarcopenic mice https://agingresearch.news/p/MED-42801617/opengraph-image/card https://agingresearch.news/p/MED-42794935 2026-10-02T23:54:54.958Z AgingResearch.News en 2026-10-02T23:54:54.958Z Raising H3K9 methylation curbs leukemic stem cell proliferation https://agingresearch.news/p/MED-42794935/opengraph-image/card https://agingresearch.news/p/MED-42794664 2026-10-02T23:54:54.716Z AgingResearch.News en 2026-10-02T23:54:54.716Z Loss of adenosine deaminase impairs DNA repair and triggers astrocyte senescence in ALS https://agingresearch.news/p/MED-42794664/opengraph-image/card https://agingresearch.news/p/MED-42801622 2026-10-02T23:54:49.757Z AgingResearch.News en 2026-10-02T23:54:49.757Z Salvianolic acid A eases atherosclerosis in mice by eliminating senescent vascular cells https://agingresearch.news/p/MED-42801622/opengraph-image/card https://agingresearch.news/p/MED-42801535 2026-10-02T23:54:49.540Z AgingResearch.News en 2026-10-02T23:54:49.540Z Synthetic gene circuit clears protein aggregates and extends lifespan in Huntington disease mice https://agingresearch.news/p/MED-42801535/opengraph-image/card https://agingresearch.news/p/MED-42802286 2026-10-02T23:54:48.770Z AgingResearch.News en 2026-10-02T23:54:48.770Z Loss of PP4 drives airway senescence through endoplasmic reticulum stress https://agingresearch.news/p/MED-42802286/opengraph-image/card https://agingresearch.news/p/MED-42800918 2026-10-02T23:54:48.148Z AgingResearch.News en 2026-10-02T23:54:48.148Z Bone-targeted exosomes delivering betaine reverse bone loss in osteoporotic rats https://agingresearch.news/p/MED-42800918/opengraph-image/card https://agingresearch.news/p/MED-42801545 2026-10-02T23:50:07.381Z AgingResearch.News en 2026-10-02T23:50:07.381Z Targeted nanoplatform reduces microglial senescence and eases motor deficits in Parkinson mice https://agingresearch.news/p/MED-42801545/opengraph-image/card https://agingresearch.news/p/MED-42801693 2026-10-02T23:50:06.902Z AgingResearch.News en 2026-10-02T23:50:06.902Z Zinc influx promotes mitophagy to slow intervertebral disc degeneration https://agingresearch.news/p/MED-42801693/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328602 2026-10-02T23:50:04.326Z AgingResearch.News en 2026-10-02T23:50:04.326Z TFAM deficiency in T cells worsens viral lung pathology and weakens immunity https://agingresearch.news/p/PPR-PPR1328602/opengraph-image/card https://agingresearch.news/p/MED-42801580 2026-10-02T23:50:01.884Z AgingResearch.News en 2026-10-02T23:50:01.884Z Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling https://agingresearch.news/p/MED-42801580/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329609 2026-10-02T23:50:00.012Z AgingResearch.News en 2026-10-02T23:50:00.012Z Single-cell foundation models show task-dependent utility for aging biology research https://agingresearch.news/p/PPR-PPR1329609/opengraph-image/card https://agingresearch.news/p/MED-42804097 2026-10-02T23:49:57.895Z AgingResearch.News en 2026-10-02T23:49:57.895Z NLRP3 inflammasome activity shifts toward regulating cell fate in aged macrophages https://agingresearch.news/p/MED-42804097/opengraph-image/card https://agingresearch.news/p/MED-42804118 2026-10-02T23:49:57.856Z AgingResearch.News en 2026-10-02T23:49:57.856Z Dual cognitive and motor training improves cognitive function in aging rats https://agingresearch.news/p/MED-42804118/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329338 2026-10-02T23:49:54.623Z AgingResearch.News en 2026-10-02T23:49:54.623Z Alternative polyadenylation regulates mitochondrial sod2 during yeast quiescence transitions https://agingresearch.news/p/PPR-PPR1329338/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329099 2026-10-02T23:49:52.355Z AgingResearch.News en 2026-10-02T23:49:52.355Z Rapamycin slows pulmonary fibrosis by reducing lung epithelial cell senescence in mice https://agingresearch.news/p/PPR-PPR1329099/opengraph-image/card https://agingresearch.news/p/MED-42805582 2026-10-02T23:49:51.094Z AgingResearch.News en 2026-10-02T23:49:51.094Z Persistent interferon-gamma fuels chronic cardiac remodeling after heart attacks in aged mice https://agingresearch.news/p/MED-42805582/opengraph-image/card https://agingresearch.news/p/MED-42803697 2026-10-02T23:49:49.723Z AgingResearch.News en 2026-10-02T23:49:49.723Z A magnesium-phenolic hydrogel accelerates wound healing in aged mice https://agingresearch.news/p/MED-42803697/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329552 2026-10-02T23:45:04.325Z AgingResearch.News en 2026-10-02T23:45:04.325Z Senescent CD8 T cells show elevated KRAS in premature coronary artery disease https://agingresearch.news/p/PPR-PPR1329552/opengraph-image/card https://agingresearch.news/p/MED-42806811 2026-10-02T23:45:03.523Z AgingResearch.News en 2026-10-02T23:45:03.523Z Krüppel-like factors modulate SKN-1 activity and lipid balance to control worm lifespan https://agingresearch.news/p/MED-42806811/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329575 2026-10-02T23:45:02.600Z AgingResearch.News en 2026-10-02T23:45:02.600Z Resistance exercise shifts muscle progenitor cells to support growth in older adults https://agingresearch.news/p/PPR-PPR1329575/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328848 2026-10-02T23:45:02.340Z AgingResearch.News en 2026-10-02T23:45:02.340Z Crebanine protects aged rats from anesthesia-induced cognitive deficits by restoring mitophagy https://agingresearch.news/p/PPR-PPR1328848/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329184 2026-10-02T23:44:56.056Z AgingResearch.News en 2026-10-02T23:44:56.056Z Brain and pituitary gene regulation links to the timing of natural menopause https://agingresearch.news/p/PPR-PPR1329184/opengraph-image/card https://agingresearch.news/p/MED-42806154 2026-10-02T23:44:56.029Z AgingResearch.News en 2026-10-02T23:44:56.029Z UHRF1 levels drive distinct senescent states in zebrafish liver cells https://agingresearch.news/p/MED-42806154/opengraph-image/card https://agingresearch.news/p/MED-42806159 2026-10-02T23:44:55.573Z AgingResearch.News en 2026-10-02T23:44:55.573Z Excess linear ubiquitination disrupts aggregate clearance and impairs proteostasis in cells https://agingresearch.news/p/MED-42806159/opengraph-image/card https://agingresearch.news/p/MED-42803875 2026-10-02T23:44:55.413Z AgingResearch.News en 2026-10-02T23:44:55.413Z Chronic stress accelerates Alzheimer pathology in mice by hyperactivating mTORC1 https://agingresearch.news/p/MED-42803875/opengraph-image/card https://agingresearch.news/p/MED-42804638 2026-10-02T23:44:50.372Z AgingResearch.News en 2026-10-02T23:44:50.372Z Astrocytic BAG3 regulates protein clearance systems linked to Alzheimer disease https://agingresearch.news/p/MED-42804638/opengraph-image/card https://agingresearch.news/p/MED-42806619 2026-10-02T23:44:49.774Z AgingResearch.News en 2026-10-02T23:44:49.774Z Circulating alpha-synuclein promotes atherosclerosis by impairing macrophage autophagy https://agingresearch.news/p/MED-42806619/opengraph-image/card https://agingresearch.news/p/MED-42805460 2026-10-02T23:44:49.402Z AgingResearch.News en 2026-10-02T23:44:49.402Z Clonal blood mutations in ASXL1 associate with higher lung cancer risk https://agingresearch.news/p/MED-42805460/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329380 2026-10-02T23:44:48.299Z AgingResearch.News en 2026-10-02T23:44:48.299Z Disrupted sphingolipid metabolism drives lysosomal and mitochondrial failure in Parkinson's disease https://agingresearch.news/p/PPR-PPR1329380/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329594 2026-10-02T23:40:06.503Z AgingResearch.News en 2026-10-02T23:40:06.503Z Depp1 drives muscle loss under fasting and low oxygen in mice https://agingresearch.news/p/PPR-PPR1329594/opengraph-image/card https://agingresearch.news/p/MED-42806136 2026-10-02T23:40:05.827Z AgingResearch.News en 2026-10-02T23:40:05.827Z Peripheral immune cell profiles predict cognitive decline in older adults https://agingresearch.news/p/MED-42806136/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329300 2026-10-02T23:40:03.460Z AgingResearch.News en 2026-10-02T23:40:03.460Z Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice https://agingresearch.news/p/PPR-PPR1329300/opengraph-image/card https://agingresearch.news/p/MED-42809424 2026-10-02T23:40:02.525Z AgingResearch.News en 2026-10-02T23:40:02.525Z Older adults with preserved cognition show slower biological aging and longer telomeres https://agingresearch.news/p/MED-42809424/opengraph-image/card https://agingresearch.news/p/MED-42808563 2026-10-02T23:39:59.302Z AgingResearch.News en 2026-10-02T23:39:59.302Z Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice https://agingresearch.news/p/MED-42808563/opengraph-image/card https://agingresearch.news/p/MED-42811753 2026-10-02T23:39:58.820Z AgingResearch.News en 2026-10-02T23:39:58.820Z 4-Octyl itaconate restores parotid gland function in aging mice https://agingresearch.news/p/MED-42811753/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330829 2026-10-02T23:39:56.016Z AgingResearch.News en 2026-10-02T23:39:56.016Z Early social isolation accelerates TDP-43 neurodegeneration and shortens lifespan in fruit flies https://agingresearch.news/p/PPR-PPR1330829/opengraph-image/card https://agingresearch.news/p/MED-42807006 2026-10-02T23:39:55.199Z AgingResearch.News en 2026-10-02T23:39:55.199Z Arterial stiffness increases sarcopenia risk partly through accelerated biological aging https://agingresearch.news/p/MED-42807006/opengraph-image/card https://agingresearch.news/p/MED-42808449 2026-10-02T23:39:52.684Z AgingResearch.News en 2026-10-02T23:39:52.684Z Telomere attrition marks disease severity in chronic cholestatic liver diseases https://agingresearch.news/p/MED-42808449/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330167 2026-10-02T23:39:51.511Z AgingResearch.News en 2026-10-02T23:39:51.511Z Exercise protects mouse hearts from chemotherapy toxicity by suppressing cellular senescence https://agingresearch.news/p/PPR-PPR1330167/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329838 2026-10-02T23:39:49.782Z AgingResearch.News en 2026-10-02T23:39:49.782Z Blood methylation framework links aging hallmarks to organ patterns across humans https://agingresearch.news/p/PPR-PPR1329838/opengraph-image/card https://agingresearch.news/p/MED-42809426 2026-10-02T23:39:49.649Z AgingResearch.News en 2026-10-02T23:39:49.649Z Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice https://agingresearch.news/p/MED-42809426/opengraph-image/card https://agingresearch.news/p/MED-42811500 2026-10-02T23:35:03.468Z AgingResearch.News en 2026-10-02T23:35:03.468Z Aging remodels mouse neutrophils across organs to drive inflammatory and senescence responses https://agingresearch.news/p/MED-42811500/opengraph-image/card https://agingresearch.news/p/MED-42810129 2026-10-02T23:35:03.392Z AgingResearch.News en 2026-10-02T23:35:03.392Z Inhalable nanoliposomes target senescence and overcome chemoresistance in mouse lung cancer https://agingresearch.news/p/MED-42810129/opengraph-image/card https://agingresearch.news/p/MED-42811583 2026-10-02T23:35:03.323Z AgingResearch.News en 2026-10-02T23:35:03.323Z Human vellus hair units undergo cellular and metabolic remodeling during skin aging https://agingresearch.news/p/MED-42811583/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330685 2026-10-02T23:35:02.230Z AgingResearch.News en 2026-10-02T23:35:02.230Z A PPAR-gamma counterpart protects worm neurons by coordinating lipids and mitochondria https://agingresearch.news/p/PPR-PPR1330685/opengraph-image/card https://agingresearch.news/p/MED-42811169 2026-10-02T23:34:57.032Z AgingResearch.News en 2026-10-02T23:34:57.032Z Alpha-synuclein impairs triglyceride metabolism and mitochondrial structure in aging nematodes https://agingresearch.news/p/MED-42811169/opengraph-image/card https://agingresearch.news/p/MED-42811497 2026-10-02T23:34:56.602Z AgingResearch.News en 2026-10-02T23:34:56.602Z Parthenolide reduces senescence and skin fibrosis in scleroderma models https://agingresearch.news/p/MED-42811497/opengraph-image/card https://agingresearch.news/p/MED-42817159 2026-10-02T23:34:56.289Z AgingResearch.News en 2026-10-02T23:34:56.289Z Interleukin-17A drives joint chondrocyte senescence through mitochondrial dysfunction in mice https://agingresearch.news/p/MED-42817159/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330646 2026-10-02T23:34:55.567Z AgingResearch.News en 2026-10-02T23:34:55.567Z Astrocytic secretome enhances hippocampal neurogenesis and spatial memory in mice https://agingresearch.news/p/PPR-PPR1330646/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331715 2026-10-02T23:34:49.854Z AgingResearch.News en 2026-10-02T23:34:49.854Z AMPK lengthens the circadian clock period through NAD+-dependent regulation of Bmal1 https://agingresearch.news/p/PPR-PPR1331715/opengraph-image/card https://agingresearch.news/p/MED-42815049 2026-10-02T23:34:49.718Z AgingResearch.News en 2026-10-02T23:34:49.718Z FOXO3 overexpression delays primordial follicle activation in chickens https://agingresearch.news/p/MED-42815049/opengraph-image/card https://agingresearch.news/p/MED-42817627 2026-10-02T23:34:49.224Z AgingResearch.News en 2026-10-02T23:34:49.224Z Nematode heat-shock protein HSP-12.6 selectively protects muscle thick filaments in vivo https://agingresearch.news/p/MED-42817627/opengraph-image/card https://agingresearch.news/p/MED-42816032 2026-10-02T23:34:49.132Z AgingResearch.News en 2026-10-02T23:34:49.132Z Icariin improves cognition and reduces neuroinflammation by promoting mitophagy in mice https://agingresearch.news/p/MED-42816032/opengraph-image/card https://agingresearch.news/p/MED-42815273 2026-10-02T23:30:08.546Z AgingResearch.News en 2026-10-02T23:30:08.546Z Accelerated biological aging links to higher gout risk and increased mortality https://agingresearch.news/p/MED-42815273/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331547 2026-10-02T23:30:05.363Z AgingResearch.News en 2026-10-02T23:30:05.363Z Blood methylation framework maps dependencies between aging hallmarks and organ aging https://agingresearch.news/p/PPR-PPR1331547/opengraph-image/card https://agingresearch.news/p/MED-42814474 2026-10-02T23:30:02.932Z AgingResearch.News en 2026-10-02T23:30:02.932Z Ultrasound-activated quantum biomaterial pairs with senolytic to suppress colorectal cancer https://agingresearch.news/p/MED-42814474/opengraph-image/card https://agingresearch.news/p/MED-42817007 2026-10-02T23:30:01.913Z AgingResearch.News en 2026-10-02T23:30:01.913Z Hybrid extracellular vesicles protect mouse skin from ultraviolet B photoaging https://agingresearch.news/p/MED-42817007/opengraph-image/card https://agingresearch.news/p/MED-42816949 2026-10-02T23:30:01.155Z AgingResearch.News en 2026-10-02T23:30:01.155Z Biomimetic nanozymes reduce neuroinflammation and cognitive decline in aged mice https://agingresearch.news/p/MED-42816949/opengraph-image/card https://agingresearch.news/p/MED-42815214 2026-10-02T23:29:57.715Z AgingResearch.News en 2026-10-02T23:29:57.715Z Electrocardiogram heart age reflects past electrical burden but not future aging pace https://agingresearch.news/p/MED-42815214/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331659 2026-10-02T23:29:56.215Z AgingResearch.News en 2026-10-02T23:29:56.215Z Stress and recovery dynamics reveal transcriptomic stability limits across aging mouse organs https://agingresearch.news/p/PPR-PPR1331659/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331635 2026-10-02T23:29:55.059Z AgingResearch.News en 2026-10-02T23:29:55.059Z Cathelicidin peptide aids fracture healing in young mice but impairs it in aged mice https://agingresearch.news/p/PPR-PPR1331635/opengraph-image/card https://agingresearch.news/p/MED-42824700 2026-10-02T23:29:54.375Z AgingResearch.News en 2026-10-02T23:29:54.375Z Gastrodia elata polysaccharide extends worm lifespan and mitigates age-related deficits in mice https://agingresearch.news/p/MED-42824700/opengraph-image/card https://agingresearch.news/p/BIORXIV-2026.09.30.755771 2026-10-02T23:29:50.633Z AgingResearch.News en 2026-10-02T23:29:50.633Z Simulated microgravity increases transcriptomic age in human organoids https://agingresearch.news/p/BIORXIV-2026.09.30.755771/opengraph-image/card https://agingresearch.news/p/BIORXIV-2026.09.30.755414 2026-10-02T23:29:48.766Z AgingResearch.News en 2026-10-02T23:29:48.766Z Rank normalization resolves distinct proteome degradation pathways in cultured cells https://agingresearch.news/p/BIORXIV-2026.09.30.755414/opengraph-image/card https://agingresearch.news/p/MED-42816597 2026-10-02T23:29:48.498Z AgingResearch.News en 2026-10-02T23:29:48.498Z Circadian E3 ligase FBXL21 regulates daily muscle proteostasis by targeting DNAJB6 https://agingresearch.news/p/MED-42816597/opengraph-image/card https://agingresearch.news/p/MED-42824422 2026-10-02T23:25:06.162Z AgingResearch.News en 2026-10-02T23:25:06.162Z Melissic acid reduces senescence in human stem cells via cAMP signaling https://agingresearch.news/p/MED-42824422/opengraph-image/card https://agingresearch.news/p/BIORXIV-2026.09.30.755827 2026-10-02T23:25:04.974Z AgingResearch.News en 2026-10-02T23:25:04.974Z Suppressing neuronal dENL/AF9 shifts metabolic and energetic profiles in aged flies https://agingresearch.news/p/BIORXIV-2026.09.30.755827/opengraph-image/card https://agingresearch.news/p/MED-42826314 2026-10-02T23:25:02.045Z AgingResearch.News en 2026-10-02T23:25:02.045Z Genetically predicted TNF-beta protects against sarcopenia traits in humans https://agingresearch.news/p/MED-42826314/opengraph-image/card https://agingresearch.news/p/MED-42825095 2026-10-02T23:25:01.961Z AgingResearch.News en 2026-10-02T23:25:01.961Z Early larval stress reduces actuarial senescence in wild marine bryozoans https://agingresearch.news/p/MED-42825095/opengraph-image/card https://agingresearch.news/p/MED-42817967 2026-10-02T23:24:59.723Z AgingResearch.News en 2026-10-02T23:24:59.723Z Neuropeptide signaling drives lipid breakdown during dietary restriction in roundworms https://agingresearch.news/p/MED-42817967/opengraph-image/card https://agingresearch.news/p/MED-42818237 2026-10-02T23:24:57.066Z AgingResearch.News en 2026-10-02T23:24:57.066Z Aging remodels skin immune responses to infection and sensitization in mice https://agingresearch.news/p/MED-42818237/opengraph-image/card https://agingresearch.news/p/MED-42825521 2026-10-02T23:24:54.648Z AgingResearch.News en 2026-10-02T23:24:54.648Z Pan-AMPK activator MK-8722 improves spatial memory in Alzheimer's model mice https://agingresearch.news/p/MED-42825521/opengraph-image/card https://agingresearch.news/p/BIORXIV-2026.09.30.755600 2026-10-02T23:24:54.632Z AgingResearch.News en 2026-10-02T23:24:54.632Z Early life stress accelerates epigenetic aging in zebra finches https://agingresearch.news/p/BIORXIV-2026.09.30.755600/opengraph-image/card https://agingresearch.news/p/MED-42818318 2026-10-02T23:24:51.744Z AgingResearch.News en 2026-10-02T23:24:51.744Z Tamoxifen causes temporary ovarian disruption without altering long-term mouse aging trajectories https://agingresearch.news/p/MED-42818318/opengraph-image/card https://agingresearch.news/p/BIORXIV-2026.09.30.754737 2026-10-02T23:24:49.952Z AgingResearch.News en 2026-10-02T23:24:49.952Z Extracellular cGAMP drives neuroinflammation and premature aging phenotypes in mice https://agingresearch.news/p/BIORXIV-2026.09.30.754737/opengraph-image/card https://agingresearch.news/p/MED-42818275 2026-10-02T23:24:48.612Z AgingResearch.News en 2026-10-02T23:24:48.612Z Microglial depletion triggers distinct molecular responses in male and female aged mouse brains https://agingresearch.news/p/MED-42818275/opengraph-image/card https://agingresearch.news/p/MED-42818253 2026-10-02T23:24:48.258Z AgingResearch.News en 2026-10-02T23:24:48.258Z Acute LINE-1 transcription remodels the molecular landscape of human fibroblasts https://agingresearch.news/p/MED-42818253/opengraph-image/card https://agingresearch.news/p/MED-42818761 2026-10-02T23:20:05.281Z AgingResearch.News en 2026-10-02T23:20:05.281Z Neural stem cell exhaustion disrupts central nervous system renewal in aging colonial chordates https://agingresearch.news/p/MED-42818761/opengraph-image/card https://agingresearch.news/p/MED-42818339 2026-10-02T23:20:02.401Z AgingResearch.News en 2026-10-02T23:20:02.401Z Altered cell communication impairs muscle recovery in older women after disuse https://agingresearch.news/p/MED-42818339/opengraph-image/card https://agingresearch.news/p/MED-42818267 2026-10-02T23:20:01.110Z AgingResearch.News en 2026-10-02T23:20:01.110Z Loss of ULK1 and ULK2 drives muscle growth in mice but impairs force https://agingresearch.news/p/MED-42818267/opengraph-image/card https://agingresearch.news/p/MED-42817945 2026-10-02T23:20:01.004Z AgingResearch.News en 2026-10-02T23:20:01.004Z Peroxisomal stress drives cellular senescence by relocating SCAF1 to mitochondria https://agingresearch.news/p/MED-42817945/opengraph-image/card https://agingresearch.news/p/MED-42817953 2026-10-02T23:19:58.210Z AgingResearch.News en 2026-10-02T23:19:58.210Z DNA methylation variability provides a distinct epigenetic marker of human aging heterogeneity https://agingresearch.news/p/MED-42817953/opengraph-image/card https://agingresearch.news/p/MED-42826099 2026-10-02T23:19:56.131Z AgingResearch.News en 2026-10-02T23:19:56.131Z Aging mouse brains accumulate myelin lipids that drive lysosomal dysfunction https://agingresearch.news/p/MED-42826099/opengraph-image/card https://agingresearch.news/p/MED-42818677 2026-10-02T23:19:55.126Z AgingResearch.News en 2026-10-02T23:19:55.126Z Brain cells organize into distinct DNA repair niches during mouse aging https://agingresearch.news/p/MED-42818677/opengraph-image/card https://agingresearch.news/p/MED-42818364 2026-10-02T23:19:54.335Z AgingResearch.News en 2026-10-02T23:19:54.335Z Transitional senescent monocytes drive age-related inflammation in humans https://agingresearch.news/p/MED-42818364/opengraph-image/card https://agingresearch.news/p/MED-42817936 2026-10-02T23:19:49.680Z AgingResearch.News en 2026-10-02T23:19:49.680Z Senescent CD4 T cells drive age-associated autoimmunity in mice and humans https://agingresearch.news/p/MED-42817936/opengraph-image/card https://agingresearch.news/p/MED-42817963 2026-10-02T23:19:49.569Z AgingResearch.News en 2026-10-02T23:19:49.569Z Single-neuron sequencing reveals widespread low-frequency somatic mutations in dementia brains https://agingresearch.news/p/MED-42817963/opengraph-image/card https://agingresearch.news/p/MED-42818326 2026-10-02T23:19:48.974Z AgingResearch.News en 2026-10-02T23:19:48.974Z Macrophage-derived VEGFA helps maintain eye fluid pressure during aging https://agingresearch.news/p/MED-42818326/opengraph-image/card https://agingresearch.news/p/MED-42826184 2026-10-02T23:19:48.277Z AgingResearch.News en 2026-10-02T23:19:48.277Z Loss of SATB1 alters 3D genome architecture in aged mouse T cells https://agingresearch.news/p/MED-42826184/opengraph-image/card https://agingresearch.news/p/MED-42818509 2026-10-02T23:15:02.577Z AgingResearch.News en 2026-10-02T23:15:02.577Z Compartment-resolved brain aging reveals distinct vascular and neurodegenerative pathways https://agingresearch.news/p/MED-42818509/opengraph-image/card https://agingresearch.news/p/MED-42818747 2026-10-02T23:15:00.432Z AgingResearch.News en 2026-10-02T23:15:00.432Z ApoD drives cellular aging phenotypes through a nuclear mechanotransduction feedback loop https://agingresearch.news/p/MED-42818747/opengraph-image/card https://agingresearch.news/p/MED-42818473 2026-10-02T23:14:59.959Z AgingResearch.News en 2026-10-02T23:14:59.959Z Ovarian stiffness and fibrosis mark reproductive aging in women https://agingresearch.news/p/MED-42818473/opengraph-image/card https://agingresearch.news/p/MED-42818675 2026-10-02T23:14:58.906Z AgingResearch.News en 2026-10-02T23:14:58.906Z Sympathetic nerve aging in mouse skin is sexually dimorphic and reversible https://agingresearch.news/p/MED-42818675/opengraph-image/card https://agingresearch.news/p/MED-42818320 2026-10-02T23:14:56.462Z AgingResearch.News en 2026-10-02T23:14:56.462Z Ovarian stiffness increases with age and tracks with declining egg yield https://agingresearch.news/p/MED-42818320/opengraph-image/card https://agingresearch.news/p/MED-42818261 2026-10-02T23:14:54.600Z AgingResearch.News en 2026-10-02T23:14:54.600Z Deleting the mechanosensitive channel Piezo1 prevents gut motility decline in aging mice https://agingresearch.news/p/MED-42818261/opengraph-image/card https://agingresearch.news/p/MED-42818259 2026-10-02T23:14:54.096Z AgingResearch.News en 2026-10-02T23:14:54.096Z Cysteine restriction extends lifespan and boosts metabolic fitness in animals https://agingresearch.news/p/MED-42818259/opengraph-image/card https://agingresearch.news/p/MED-42818871 2026-10-02T23:14:53.685Z AgingResearch.News en 2026-10-02T23:14:53.685Z Auditory nerve myelin degeneration defines a subtype of age-related hearing loss https://agingresearch.news/p/MED-42818871/opengraph-image/card https://agingresearch.news/p/MED-42818681 2026-10-02T23:14:49.522Z AgingResearch.News en 2026-10-02T23:14:49.522Z Inhibiting miR-128-3p restores muscle mass and function in aged mice https://agingresearch.news/p/MED-42818681/opengraph-image/card https://agingresearch.news/p/MED-42818845 2026-10-02T23:14:48.917Z AgingResearch.News en 2026-10-02T23:14:48.917Z Inherited genetic variants influence age-associated mosaic chromosomal errors in human blood https://agingresearch.news/p/MED-42818845/opengraph-image/card https://agingresearch.news/p/MED-42818323 2026-10-02T23:14:48.276Z AgingResearch.News en 2026-10-02T23:14:48.276Z Human neurons accumulate far more mutations over lifespan than shorter-lived mammals https://agingresearch.news/p/MED-42818323/opengraph-image/card https://agingresearch.news/p/MED-42818375 2026-10-02T23:14:47.696Z AgingResearch.News en 2026-10-02T23:14:47.696Z Dietary restriction activates autophagy through selective oxidation of ATG5 https://agingresearch.news/p/MED-42818375/opengraph-image/card https://agingresearch.news/p/MED-42814802 2026-10-02T23:10:04.494Z AgingResearch.News en 2026-10-02T23:10:04.494Z Cranial bone marrow monocytes drive brain injury inflammation and respond to fenofibrate https://agingresearch.news/p/MED-42814802/opengraph-image/card https://agingresearch.news/p/MED-42823099 2026-10-02T23:10:02.714Z AgingResearch.News en 2026-10-02T23:10:02.714Z Human lymph node fibroblasts show cellular aging features before rheumatoid arthritis onset https://agingresearch.news/p/MED-42823099/opengraph-image/card https://agingresearch.news/p/MED-42816544 2026-10-02T23:10:01.831Z AgingResearch.News en 2026-10-02T23:10:01.831Z D-allose attenuates intervertebral disc degeneration by targeting a mitochondrial stress pathway https://agingresearch.news/p/MED-42816544/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332566 2026-10-02T23:10:01.337Z AgingResearch.News en 2026-10-02T23:10:01.337Z Multi-omics analysis reveals molecular networks driving muscle decline in aging vervet monkeys https://agingresearch.news/p/PPR-PPR1332566/opengraph-image/card https://agingresearch.news/p/MED-42819224 2026-10-02T23:09:56.925Z AgingResearch.News en 2026-10-02T23:09:56.925Z Structured exercise reduces heart fat and an inflammatory marker in older adults https://agingresearch.news/p/MED-42819224/opengraph-image/card https://agingresearch.news/p/MED-42823784 2026-10-02T23:09:56.492Z AgingResearch.News en 2026-10-02T23:09:56.492Z Aging impairs blastema formation and tissue regeneration in Cladonema jellyfish https://agingresearch.news/p/MED-42823784/opengraph-image/card https://agingresearch.news/p/MED-42822391 2026-10-02T23:09:55.685Z AgingResearch.News en 2026-10-02T23:09:55.685Z Fruit flies provide an in vivo model to study ferroptosis and lifespan https://agingresearch.news/p/MED-42822391/opengraph-image/card https://agingresearch.news/p/MED-42821357 2026-10-02T23:09:55.419Z AgingResearch.News en 2026-10-02T23:09:55.419Z Aged perivascular fat increases aortic stiffness and collagen deposition in mice https://agingresearch.news/p/MED-42821357/opengraph-image/card https://agingresearch.news/p/MED-42823843 2026-10-02T23:09:49.273Z AgingResearch.News en 2026-10-02T23:09:49.273Z Deleting beta-catenin in mouse disc cells lowers inflammation and immune cell recruitment https://agingresearch.news/p/MED-42823843/opengraph-image/card https://agingresearch.news/p/MED-42822052 2026-10-02T23:09:49.233Z AgingResearch.News en 2026-10-02T23:09:49.233Z Senescent prostate cancer cells drive stromal remodeling through TGF-beta signaling https://agingresearch.news/p/MED-42822052/opengraph-image/card https://agingresearch.news/p/MED-42823972 2026-10-02T23:09:48.946Z AgingResearch.News en 2026-10-02T23:09:48.946Z Extracellular vesicle microRNA promotes muscle regeneration by suppressing AP2M1 https://agingresearch.news/p/MED-42823972/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332550 2026-10-02T23:09:48.382Z AgingResearch.News en 2026-10-02T23:09:48.382Z TET enzyme deficiency drives the selection of specific aneuploid cells in mice https://agingresearch.news/p/PPR-PPR1332550/opengraph-image/card https://agingresearch.news/p/MED-42799938 2026-10-02T22:19:00.330Z AgingResearch.News en 2026-10-02T22:19:00.330Z Aging rhesus macaques display distinct fluid proteomic signatures of senescence and neuropathology https://agingresearch.news/p/MED-42799938/opengraph-image/card https://agingresearch.news/p/MED-42805127 2026-10-02T22:18:58.208Z AgingResearch.News en 2026-10-02T22:18:58.208Z High metabolic inflammation trajectories predict faster frailty progression in older adults https://agingresearch.news/p/MED-42805127/opengraph-image/card https://agingresearch.news/p/MED-42788951 2026-10-02T22:18:53.034Z AgingResearch.News en 2026-10-02T22:18:53.034Z Lack of the AT2R receptor accelerates cardiac senescence and fibrosis in aging mice https://agingresearch.news/p/MED-42788951/opengraph-image/card https://agingresearch.news/p/MED-42810629 2026-10-02T22:18:52.670Z AgingResearch.News en 2026-10-02T22:18:52.670Z Extracellular vesicles carrying two microRNAs reduce vascular aging markers in progeria cells https://agingresearch.news/p/MED-42810629/opengraph-image/card https://agingresearch.news/p/MED-42806945 2026-10-02T22:18:51.498Z AgingResearch.News en 2026-10-02T22:18:51.498Z Ghrelin alleviates aging-related cognitive impairment by restoring microglial autophagy https://agingresearch.news/p/MED-42806945/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329344 2026-10-02T22:18:51.373Z AgingResearch.News en 2026-10-02T22:18:51.373Z Accelerated epigenetic aging predicts major depression and brain changes after trauma https://agingresearch.news/p/PPR-PPR1329344/opengraph-image/card https://agingresearch.news/p/MED-42809987 2026-10-02T22:18:46.421Z AgingResearch.News en 2026-10-02T22:18:46.421Z Engineered exosome-mimetic nanoparticles improve liver function in aged mice https://agingresearch.news/p/MED-42809987/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328141 2026-10-02T22:18:45.687Z AgingResearch.News en 2026-10-02T22:18:45.687Z DNMT3A mutations linked to clonal hematopoiesis alter macrophage epigenetics and accelerate migration https://agingresearch.news/p/PPR-PPR1328141/opengraph-image/card https://agingresearch.news/p/MED-42811603 2026-10-02T22:18:45.093Z AgingResearch.News en 2026-10-02T22:18:45.093Z Long-term human skin platform models chronic inflammation and senolytic treatments https://agingresearch.news/p/MED-42811603/opengraph-image/card https://agingresearch.news/p/MED-42794710 2026-10-02T22:18:44.058Z AgingResearch.News en 2026-10-02T22:18:44.058Z Activin A from inflammatory macrophages impairs stem cell regulation in aging human muscle https://agingresearch.news/p/MED-42794710/opengraph-image/card https://agingresearch.news/p/MED-42808804 2026-10-02T22:18:38.863Z AgingResearch.News en 2026-10-02T22:18:38.863Z IGF-1 and SLC25A33 preserve cochlear blood barrier integrity in aged mice https://agingresearch.news/p/MED-42808804/opengraph-image/card https://agingresearch.news/p/MED-42810733 2026-10-02T22:18:38.580Z AgingResearch.News en 2026-10-02T22:18:38.580Z Exercise slows epigenetic aging in breast cancer survivors https://agingresearch.news/p/MED-42810733/opengraph-image/card https://agingresearch.news/p/MED-42810392 2026-10-02T22:18:34.397Z AgingResearch.News en 2026-10-02T22:18:34.397Z Direct AMPK activation extends lifespan across yeast, worms, and flies https://agingresearch.news/p/MED-42810392/opengraph-image/card https://agingresearch.news/p/MED-42789496 2026-10-02T22:18:33.899Z AgingResearch.News en 2026-10-02T22:18:33.899Z Proteomic multi-organ aging accelerates before adverse events in heart failure patients https://agingresearch.news/p/MED-42789496/opengraph-image/card https://agingresearch.news/p/MED-42805938 2026-10-02T22:18:33.461Z AgingResearch.News en 2026-10-02T22:18:33.461Z Biological aging clocks combined with genetics improve dementia risk prediction https://agingresearch.news/p/MED-42805938/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330642 2026-10-02T22:18:32.329Z AgingResearch.News en 2026-10-02T22:18:32.329Z Failed clearance of post-ovulatory debris drives ovarian fibroinflammation in mice https://agingresearch.news/p/PPR-PPR1330642/opengraph-image/card https://agingresearch.news/p/MED-42800673 2026-10-02T22:18:27.207Z AgingResearch.News en 2026-10-02T22:18:27.207Z Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats https://agingresearch.news/p/MED-42800673/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330750 2026-10-02T22:18:26.331Z AgingResearch.News en 2026-10-02T22:18:26.331Z Elevated TNFα induces hyperreactive platelets by reprogramming hematopoietic stem cells in mice https://agingresearch.news/p/PPR-PPR1330750/opengraph-image/card https://agingresearch.news/p/MED-42791620 2026-10-02T22:18:25.620Z AgingResearch.News en 2026-10-02T22:18:25.620Z Deleting liver growth hormone receptors accelerates aging phenotypes and shortens lifespan in mice https://agingresearch.news/p/MED-42791620/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329296 2026-10-02T22:18:25.466Z AgingResearch.News en 2026-10-02T22:18:25.466Z Plasma proteins link metabolomic aging to disease and mortality in humans https://agingresearch.news/p/PPR-PPR1329296/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328120 2026-10-02T22:18:20.046Z AgingResearch.News en 2026-10-02T22:18:20.046Z Translation error rates increase during aging in post-mitotic cells https://agingresearch.news/p/PPR-PPR1328120/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330629 2026-10-02T22:18:19.544Z AgingResearch.News en 2026-10-02T22:18:19.544Z Blood and facial photos track organ aging and senescence scores in humans https://agingresearch.news/p/PPR-PPR1330629/opengraph-image/card https://agingresearch.news/p/MED-42801556 2026-10-02T22:18:17.088Z AgingResearch.News en 2026-10-02T22:18:17.088Z Protein Grtp1 protects male germlines from aging and prevents offspring behavioral deficits https://agingresearch.news/p/MED-42801556/opengraph-image/card https://agingresearch.news/p/MED-42802483 2026-10-02T22:18:16.649Z AgingResearch.News en 2026-10-02T22:18:16.649Z Autophagy flux varies by sex and cell type during human aging https://agingresearch.news/p/MED-42802483/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330713 2026-10-02T22:18:13.497Z AgingResearch.News en 2026-10-02T22:18:13.497Z Restoring HIRA chromatin maintenance improves aged mouse oocyte quality https://agingresearch.news/p/PPR-PPR1330713/opengraph-image/card https://agingresearch.news/p/MED-42789455 2026-10-02T22:18:13.487Z AgingResearch.News en 2026-10-02T22:18:13.487Z Loss of myofibril number drives muscle fibre atrophy during aging and disuse https://agingresearch.news/p/MED-42789455/opengraph-image/card https://agingresearch.news/p/PPR-PPR1330681 2026-10-02T22:18:08.412Z AgingResearch.News en 2026-10-02T22:18:08.412Z Chronological age prediction does not prove biological age measurement https://agingresearch.news/p/PPR-PPR1330681/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328027 2026-10-02T22:18:07.736Z AgingResearch.News en 2026-10-02T22:18:07.736Z Lactate receptor activation reduces cellular senescence and protects vascular health in mice https://agingresearch.news/p/PPR-PPR1328027/opengraph-image/card https://agingresearch.news/p/MED-42811122 2026-10-02T22:18:07.697Z AgingResearch.News en 2026-10-02T22:18:07.697Z Exercise-induced extracellular vesicles enhance aged cartilage health via microRNA-29 https://agingresearch.news/p/MED-42811122/opengraph-image/card https://agingresearch.news/p/MED-42786309 2026-10-02T22:18:07.189Z AgingResearch.News en 2026-10-02T22:18:07.189Z Kidney tubular epithelial cells drive accelerated epigenetic aging in disease https://agingresearch.news/p/MED-42786309/opengraph-image/card https://agingresearch.news/p/MED-42806572 2026-10-02T22:18:00.752Z AgingResearch.News en 2026-10-02T22:18:00.752Z Bispecific T cell engager eliminates senescent cells in mice and nonhuman primates https://agingresearch.news/p/MED-42806572/opengraph-image/card https://agingresearch.news/p/MED-42791602 2026-10-02T22:17:59.611Z AgingResearch.News en 2026-10-02T22:17:59.611Z A deep learning score for cellular senescence predicts human mortality and disease risk https://agingresearch.news/p/MED-42791602/opengraph-image/card https://agingresearch.news/p/MED-42786167 2026-10-02T22:17:54.319Z AgingResearch.News en 2026-10-02T22:17:54.319Z Retinal imaging model predicts age and reveals sex differences in human aging https://agingresearch.news/p/MED-42786167/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329435 2026-10-02T22:17:53.554Z AgingResearch.News en 2026-10-02T22:17:53.554Z A distinct p21-driven macrophage senotype accumulates during aging and liver disease https://agingresearch.news/p/PPR-PPR1329435/opengraph-image/card https://agingresearch.news/p/MED-42786310 2026-10-02T22:17:52.462Z AgingResearch.News en 2026-10-02T22:17:52.462Z Oral bacterium Neisseria flavescens promotes healthspan in worms and rejuvenates aged mice https://agingresearch.news/p/MED-42786310/opengraph-image/card https://agingresearch.news/p/MED-42806003 2026-10-02T22:17:52.423Z AgingResearch.News en 2026-10-02T22:17:52.423Z Macrophage CD38 drives age-related placental senescence by depleting NAD+ https://agingresearch.news/p/MED-42806003/opengraph-image/card https://agingresearch.news/p/PPR-PPR1328604 2026-10-02T22:17:47.841Z AgingResearch.News en 2026-10-02T22:17:47.841Z Early-life mitochondrial DNA mutations drive age-related pathology in mice https://agingresearch.news/p/PPR-PPR1328604/opengraph-image/card https://agingresearch.news/p/MED-42811121 2026-10-02T22:17:46.996Z AgingResearch.News en 2026-10-02T22:17:46.996Z Cardiolipin loss drives muscle fiber shifts during aging via a nuclear receptor https://agingresearch.news/p/MED-42811121/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329401 2026-10-02T22:17:46.403Z AgingResearch.News en 2026-10-02T22:17:46.403Z Biological age uncertainty independently predicts mortality and health decline in humans https://agingresearch.news/p/PPR-PPR1329401/opengraph-image/card https://agingresearch.news/p/PPR-PPR1329306 2026-10-02T22:17:45.779Z AgingResearch.News en 2026-10-02T22:17:45.779Z CAR T cells targeting inflammatory bone marrow progenitors restore cognition in aged mice https://agingresearch.news/p/PPR-PPR1329306/opengraph-image/card https://agingresearch.news/p/MED-42813517 2026-10-02T20:28:04.569Z AgingResearch.News en 2026-10-02T20:28:04.569Z Oral 4-methylumbelliferone remodels brain extracellular matrix and improves memory in aged mice https://agingresearch.news/p/MED-42813517/opengraph-image/card https://agingresearch.news/p/MED-42815787 2026-10-02T20:27:57.260Z AgingResearch.News en 2026-10-02T20:27:57.260Z Chelating intracellular calcium reduces fibroblast senescence and eases lung fibrosis https://agingresearch.news/p/MED-42815787/opengraph-image/card https://agingresearch.news/p/MED-42815968 2026-10-02T20:27:54.929Z AgingResearch.News en 2026-10-02T20:27:54.929Z Dietary iron links to slower biological aging while high supplement doses accelerate it https://agingresearch.news/p/MED-42815968/opengraph-image/card https://agingresearch.news/p/MED-42816034 2026-10-02T20:27:51.124Z AgingResearch.News en 2026-10-02T20:27:51.124Z Syringin reduces cellular senescence and pulmonary fibrosis in mice and cell models https://agingresearch.news/p/MED-42816034/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331102 2026-10-02T20:27:49.382Z AgingResearch.News en 2026-10-02T20:27:49.382Z Gut microbes from hearing loss patients trigger inner ear damage in young mice https://agingresearch.news/p/PPR-PPR1331102/opengraph-image/card https://agingresearch.news/p/MED-42816559 2026-10-02T20:27:48.646Z AgingResearch.News en 2026-10-02T20:27:48.646Z Mammalian cellular identity erodes with age through predictable chromatin drift https://agingresearch.news/p/MED-42816559/opengraph-image/card https://agingresearch.news/p/MED-42823846 2026-10-02T20:27:47.018Z AgingResearch.News en 2026-10-02T20:27:47.018Z Proteomic organ clocks predict mortality but trail established physiological and epigenetic biomarkers https://agingresearch.news/p/MED-42823846/opengraph-image/card https://agingresearch.news/p/MED-42814579 2026-10-02T20:27:43.408Z AgingResearch.News en 2026-10-02T20:27:43.408Z Fetal gene Lin28b improves ex vivo expansion of aged mouse blood stem cells https://agingresearch.news/p/MED-42814579/opengraph-image/card https://agingresearch.news/p/MED-42815479 2026-10-02T20:27:41.779Z AgingResearch.News en 2026-10-02T20:27:41.779Z Loss of the lipid enzyme PNPLA7 impairs skeletal muscle and mitochondria in mice https://agingresearch.news/p/MED-42815479/opengraph-image/card https://agingresearch.news/p/MED-42814573 2026-10-02T20:27:41.414Z AgingResearch.News en 2026-10-02T20:27:41.414Z USP-48 modulates mitochondrial stress and enables longevity in low-insulin worms https://agingresearch.news/p/MED-42814573/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331620 2026-10-02T20:27:40.416Z AgingResearch.News en 2026-10-02T20:27:40.416Z Epigenetic puberty index tracks biological aging and adult health risks https://agingresearch.news/p/PPR-PPR1331620/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331648 2026-10-02T20:27:34.615Z AgingResearch.News en 2026-10-02T20:27:34.615Z Mechanistic biological age clock matches PhenoAge in predicting human mortality https://agingresearch.news/p/PPR-PPR1331648/opengraph-image/card https://agingresearch.news/p/MED-42814817 2026-10-02T20:27:32.738Z AgingResearch.News en 2026-10-02T20:27:32.738Z Transcriptomic longevity modules predict life span-extending compounds in roundworms https://agingresearch.news/p/MED-42814817/opengraph-image/card https://agingresearch.news/p/MED-42814823 2026-10-02T20:27:28.306Z AgingResearch.News en 2026-10-02T20:27:28.306Z Speech clocks reflect dementia phenotypes and biological aging markers https://agingresearch.news/p/MED-42814823/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331631 2026-10-02T20:27:26.820Z AgingResearch.News en 2026-10-02T20:27:26.820Z Chemogenetic hydrogen sulfide production reverses vascular remodeling in aged mice https://agingresearch.news/p/PPR-PPR1331631/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331792 2026-10-02T20:27:26.811Z AgingResearch.News en 2026-10-02T20:27:26.811Z ASXL1 mutations in clonal hematopoiesis accelerate aortic valve calcification https://agingresearch.news/p/PPR-PPR1331792/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331578 2026-10-02T20:27:25.763Z AgingResearch.News en 2026-10-02T20:27:25.763Z Impaired glymphatic clearance links inflammation to accelerated brain aging in schizophrenia https://agingresearch.news/p/PPR-PPR1331578/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331651 2026-10-02T20:27:21.045Z AgingResearch.News en 2026-10-02T20:27:21.045Z Declining ribosome function drives reproductive aging in fruit fly and mouse oocytes https://agingresearch.news/p/PPR-PPR1331651/opengraph-image/card https://agingresearch.news/p/MED-42816584 2026-10-02T20:27:20.706Z AgingResearch.News en 2026-10-02T20:27:20.706Z Clonal hematopoiesis remodels human bone marrow into an inflammatory prefibrotic environment https://agingresearch.news/p/MED-42816584/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331665 2026-10-02T20:27:20.442Z AgingResearch.News en 2026-10-02T20:27:20.442Z Androgen receptor polyglutamine tract controls muscle growth and atrophy pathways https://agingresearch.news/p/PPR-PPR1331665/opengraph-image/card https://agingresearch.news/p/PPR-PPR1331023 2026-10-02T20:27:19.958Z AgingResearch.News en 2026-10-02T20:27:19.958Z Organ age acceleration and mortality risk reflect distinct biological processes https://agingresearch.news/p/PPR-PPR1331023/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332616 2026-10-02T20:25:20.633Z AgingResearch.News en 2026-10-02T20:25:20.633Z Inhibiting CHK2 improves oocyte quality and reduces ovarian inflammation in aged mice https://agingresearch.news/p/PPR-PPR1332616/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332602 2026-10-02T20:25:19.752Z AgingResearch.News en 2026-10-02T20:25:19.752Z Nucleoli buffer displaced heterochromatin to limit premature aging programs in cells https://agingresearch.news/p/PPR-PPR1332602/opengraph-image/card https://agingresearch.news/p/MED-42823831 2026-10-02T20:25:16.272Z AgingResearch.News en 2026-10-02T20:25:16.272Z Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice https://agingresearch.news/p/MED-42823831/opengraph-image/card https://agingresearch.news/p/MED-42823742 2026-10-02T20:25:15.017Z AgingResearch.News en 2026-10-02T20:25:15.017Z Blood cell composition explains substantial variation in DNA methylation age https://agingresearch.news/p/MED-42823742/opengraph-image/card https://agingresearch.news/p/MED-42816477 2026-10-02T20:25:13.186Z AgingResearch.News en 2026-10-02T20:25:13.186Z Base editing of the lamin farnesylation motif rescues progeria phenotypes in organoids https://agingresearch.news/p/MED-42816477/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332504 2026-10-02T20:25:12.650Z AgingResearch.News en 2026-10-02T20:25:12.650Z DNA methylation proxies of senescence markers track human disease and mortality https://agingresearch.news/p/PPR-PPR1332504/opengraph-image/card https://agingresearch.news/p/MED-42823536 2026-10-02T20:25:08.522Z AgingResearch.News en 2026-10-02T20:25:08.522Z Dasatinib and quercetin reduce liver fibrosis in a phase-2 MASH trial https://agingresearch.news/p/MED-42823536/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332575 2026-10-02T20:25:07.428Z AgingResearch.News en 2026-10-02T20:25:07.428Z Directly converted human neuronal spheroids preserve donor age and model Alzheimer disease https://agingresearch.news/p/PPR-PPR1332575/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332509 2026-10-02T20:25:06.810Z AgingResearch.News en 2026-10-02T20:25:06.810Z Somatic blood mutations associate with accelerated frailty and functional decline in humans https://agingresearch.news/p/PPR-PPR1332509/opengraph-image/card https://agingresearch.news/p/PPR-PPR1332680 2026-10-02T20:25:05.784Z AgingResearch.News en 2026-10-02T20:25:05.784Z Engineered cardiac transcription factor restores vision and reduces frailty in aging mice https://agingresearch.news/p/PPR-PPR1332680/opengraph-image/card